Synthetic cannabinoidsHuffman, an organic chemist at Clemson University. Over the course of twenty years, Huffman and his team developed synthetic cannabinoid compounds which were used to test the effect of cannabinoid receptors in the brain and other organs. In spice legal high wikipedia, JHW compounds began tbol experience in Germany initially can you buy dianabol in australia a marijuana alternatives known as s pice. Subsequent government regulations in the United States and many other countries banning JWH have given birth to monster versions of John W. Government regulations were in spice legal high wikipedia to be blamed for the rise of the so called monster chemicals being now used in modern day spice versions, however, producers of these products who care little for the welfare of their clientele are also to be blamed for the rise in emergency room visits by spice legal high wikipedia. Synthetic cannabinoids have euphoric and psychoactive effects on the user, very much like those of natural marijuana. However, there are other effects associated with the synthetic versions of marijuana, some of which may be especially dangerous.
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HU is a synthetic cannabinoid that was first synthesized in from 1R,5S -myrtenol  by a group led by Professor Raphael Mechoulam at the Hebrew University. The abbreviation "HU" stands for Hebrew University.
It was also indicated by this increased neural growth to entail antianxiety and antidepressant effects. HU, alongside other synthetic cannabinoids like WIN 55, and JWH , is implicated in preventing the inflammation caused by amyloid beta proteins involved in Alzheimer's disease , in addition to preventing cognitive impairment and loss of neuronal markers.
This anti-inflammatory action is induced through the activation of cannabinoid receptors , which prevents microglial activation that elicits the inflammation. In addition, cannabinoids completely abolish neurotoxicity related to microglia activation in rat models. HU is a potent analgesic with many of the same effects as natural THC. HU is the enantiomer of HU Dexanabinol.
The original synthesis of HU is based on an acid-catalyzed condensation of — - Myrtenol and 1,1-Dimethylheptylresorcinol 3,5-Dihydroxy 1,1-dimethylheptyl benzol. According to the U. HU is not listed in the schedules set out by the United Nations ' Single Convention on Narcotic Drugs from nor their Convention on Psychotropic Substances from ,  so the signatory countries to these international drug control treaties are not required by said treaties to control HU HU is banned in New Zealand as of 8 May HU is not listed in the list of scheduled controlled substances in the USA.
An elucidation of the rationale for the DEA's claim was not presented, no references were cited, and the claim was eventually removed from the DEA's website. HU is a Schedule I controlled substance in Alabama. A synthetic controlled substance that is any material, mixture, or preparation that contains any quantity of the following chemical compounds, their salts, isomers and salts of isomers, unless specifically excepted, whenever the existence of these salts, isomers and salts of isomers is possible within the specific chemical designation or compound:.
HU is a Schedule I controlled substance , categorized as a hallucinogen , making it illegal to buy, sell, or possess in the state of Florida without a license. HU [ 6aR,10aR Hydroxymethyl -6,6-dimethyl 2-methyloctanyl -6a,7,10,10a-tetrahydrobenzo[c]chromenol]. Structural classes include but are not limited to:. From Wikipedia, the free encyclopedia. Vol 1, No 5. Pharmacology Biochemistry and Behavior.
The Journal of Pharmacology and Experimental Therapeutics. Journal of Medicinal Chemistry. The Journal of Clinical Investigation. Asymmetry , 5, Understanding the 'Spice' phenomenon" PDF. Archived from the original on Retrieved 2 February Cannabinoid receptor modulators cannabinoids by pharmacology List of: Diphenidine Ephenidine Fluorolintane Methoxphenidine. Dextrallorphan Dextromethorphan Dextrorphan Racemethorphan Racemorphan.
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