Clobetasol Propionate Metabolism

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  • Clobetasol
  • Clobetasol propionate | C25H32ClFO5 - PubChem
  • Clobetasol propionate - DrugBank
  • Clobetasol - Wikipedia
  • Clobetasol propionate

    Clobetasol

    clobetasol propionate metabolism Available forms Available by prescription only Cream: Apply a thin layer to affected skin areas b. Limit treatment to 14 days, with no more than 50 sustanon and testoviron cycle of the cream or ointment or 50 ml of lotion 25 mg total weekly. Inflammation and pruritus clobetasol propionate metabolism moderate to severe corticosteroid-responsive dermatoses of the scalp. Apply to affected scalp area twice daily, once in the morning and once at night. Invert can and dispense clobftasol amount of Olux foam to a maximum of a golf-ball-size dollop into the cap of can, onto a saucer or other cool surface, or directly on the lesion, taking care to avoid contact with the clobetasol propionate metabolism.

    Clobetasol propionate | C25H32ClFO5 - PubChem

    clobetasol propionate metabolism

    Available forms Available by prescription only Cream: Apply a thin layer to affected skin areas b. Limit treatment to 14 days, with no more than 50 g of the cream or ointment or 50 ml of lotion 25 mg total weekly. Inflammation and pruritus of moderate to severe corticosteroid-responsive dermatoses of the scalp. Apply to affected scalp area twice daily, once in the morning and once at night.

    Invert can and dispense small amount of Olux foam to a maximum of a golf-ball-size dollop into the cap of can, onto a saucer or other cool surface, or directly on the lesion, taking care to avoid contact with the eyes. Move hair away from affected scalp area so that the foam can be applied to each affected area. Gently massage into affected area until the foam disappears.

    Repeat until entire affected scalp area is treated. Limit treatment to 14 days, with no more than 50 g of foam weekly. Drug is effective because of anti-inflammatory, antipruritic, and vasoconstrictive actions; however, the exact mechanism of its actions is unknown. Amount absorbed depends on the potency of the preparation, the amount applied, and the nature of the skin at the application site. Absorption increases in areas of skin damage, inflammation, or occlusion.

    Some systemic absorption of topical corticosteroids occurs, especially through the oral mucosa. After topical application, clobetasol is distributed throughout the local skin. Any drug absorbed into the circulation is rapidly removed from the blood and distributed into muscle, liver, skin, intestines, and kidneys. After topical administration, drug is metabolized primarily in the skin. The small amount absorbed into systemic circulation is metabolized primarily in the liver to inactive compounds.

    Inactive metabolites are excreted by the kidneys, primarily as glucuronides and sulfates, but also as unconjugated products. Small amounts of the metabolites also are excreted in feces. Contraindications and precautions Contraindicated in patients hypersensitive to corticosteroids. Overdose and treatment No information available. Intermittent use prevents cumulative effects. Drug suppresses HPA axis at doses as low as 2 g daily.

    Avoid flame and smoking during and immediately following application.

    Clobetasol propionate - DrugBank

    clobetasol propionate metabolism

    Clobetasol - Wikipedia

    clobetasol propionate metabolism

    clobetasol propionate metabolism