Invalid URLOk so I saw my new dr today and I absolutely love her!! She went though my history and did my physical. My RE had been pushing me to do IVF with donor eggs without giving me a reason other than no viable pregnancy in 1 year. So she was my second opinion. Anyways she said we could try different meds and steroids.
Medications That Can Affect Fertility - Parents
When it comes to fertility medication, some are more controversial than others. A steroid called Prednisolone, marketed as Prednisone in a few countries, is one of them. Some call it a fertility wonder drug. Others are more sceptical. So is it worth trying or a waste of money? Prednisolone is basically a synthetic hormone that helps suppress immune responses.
Its anti-inflammatory and immuno-suppressive abilities can treat a range of other conditions, including allergies, blood disorders, respiratory problems and skin problems. But while Prednisolone is well regarded in general medicine, the jury is out on its benefits to fertility patients. Lord Winston , for example, is distinctly wary of it.
But most are small-scale. As yet, no extensive trials have been conducted. An Australian study used low-dose Prednisolone alongside blood-thinner Clexane to try to suppress natural killer cells in women with recurrent miscarriages. The results were quite promising. But the number of participants involved was minimal, making it hard to draw firm conclusions. And a update of a Cochrane Review into immunotherapy for recurrent miscarriage had to exclude a number of studies into Prednisolone from analysis.
When prescribed to female fertility patients, Prednisolone is used for a relatively short period of time. Doses vary, but 5 mg a day is common. Be wary if your clinic increases that daily dose, especially if it goes above 20 mg. Prednisolone pills are normally started on egg retrieval day. But patients with elevated NK levels, or a pattern of implantation failure after fertility treatments, may be put on the drug when they start their stimulating medication.
If your HCG blood test is negative, your fertility medication, including Prednisolone, will be stopped. Your dosage may be gradually reduced. Like any drug, there are risks involved with taking steroids. Common side effects of Prednisolone include irritability, anxiety and sleep disturbance.
Taking corticosteroids in pregnancy could also affect fetal growth. We can only hope the claimed benefits are worth that risk. Deciding whether or not to try a fertility drug like Prednisolone is not easy. On the other, it may be a dead end. Talk to your GP and clinic.
The success stories on the fertility forums may sound enticing. And until a large-scale, randomised, controlled trial is carried out, the situation remains unclear. I have been trying to conceive for 10 years now, I have pcos, I have never received any fertility treatment, nor have I ever been pregnant, that was until December when I fell pregnant whilst taking prednisone, sadly that pregnancy ended in miscarriage at 8 weeks.
I was only in Prednisone for 10 days for a chest infection so I never expected it would help me get pregnant. I have told my doctor that when I got pregnant I was on prednisone but they refuse to prescribe it me and they are well aware of my struggle to get pregnant.
I have not been able to get pregnant since, no offer of help or any interest from Doctors of my fertility. If ever there comes up any trials to help women get pregnant on prednisone then I would happily put myself forward for it. I am saving up for surrogacy but if I can get pregnant naturally by taking prednisone then I would happily go for It. Hi pagan, M Dr Devendra from India.
I m a gynecologist.. I want to tell u one thing if u have got pregnant once half d battle u have won…it means there is nothing wrong in d process of fertilization and implantation.. I am currently taking prednisone 20mg tablets. I have been married 16yrs, and we have been trying for 14yrs to conceive, been on numerous cycles of Clomid, had a couple of Hysterosalpingogram done, had my uterus and ovaries checked with ultrasound, every test an procedure I have done have all come back normal.
Only explanation I have been given, unexplainable, but see nothing wrong for us to conceive. In conclusion, can I continue with taking and finishing the prednisone that I am on, and engage in intercourse with my husband?
This week I should be ovulating, according to the period diary app I use. I was not made aware by my gynecologist that this was a steroid nor the side effects until I researched. I plan on going to another as there has to be a better and safer option. Hello , i just wondering this is right that doctor after IVF tell me to take 2 time a day prenisolone and how this tablets can effect my pregnacy? Hi Ren, just wondering how are you doing with your IVF?