Mineralocorticoid Wiki

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  • Category:Mineralocorticoids
  • Glucocorticoid - Wikipedia
  • Mineralocorticoid - Wikipedia
  • Mineralocorticoid receptor - Wikipedia
  • all_steroid_drugs [TUSOM | Pharmwiki]
  • What does aldosterone mean?

    Category:Mineralocorticoids

    mineralocorticoid wiki MR is a receptor with equal affinity for mineralocorticoids and glucocorticoids. It belongs to the nuclear receptor family where the ligand diffuses into cells, interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus. MR is expressed in many tissues, such as the kidney mineralocorticoid wiki, colonheartmineraloocrticoid nervous system hippocampus mineralocorticoid wiki, brown adipose tissue and sweat glands. The receptor is activated by mineralocorticoids such as aldosterone and its mineralocorticoid wiki deoxycorticosterone as well as glucocorticoidslike cortisol. In intact animals, the mineralocorticoid wiki receptor is "protected" from glucocorticoids by co-localization of an enzyme, Corticosteroid beta-dehydrogenase isozyme 2 a.

    Glucocorticoid - Wikipedia

    mineralocorticoid wiki

    MR is a receptor with equal affinity for mineralocorticoids and glucocorticoids. It belongs to the nuclear receptor family where the ligand diffuses into cells, interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus. MR is expressed in many tissues, such as the kidney , colon , heart , central nervous system hippocampus , brown adipose tissue and sweat glands.

    The receptor is activated by mineralocorticoids such as aldosterone and its precursor deoxycorticosterone as well as glucocorticoids , like cortisol. In intact animals, the mineralocorticoid receptor is "protected" from glucocorticoids by co-localization of an enzyme, Corticosteroid beta-dehydrogenase isozyme 2 a.

    It also responds to some progestins. Spironolactone and eplerenone are steroidal MR antagonists of the spirolactone group. Activation of the mineralocorticoid receptor, upon the binding of its ligand aldosterone, results in its translocation to the cell nucleus, homodimerization and binding to hormone response elements present in the promoter of some genes.

    This results in the complex recruitment of the transcriptional machinery and the transcription into mRNA of the DNA sequence of the activated genes. Mineralocorticoid receptor has been shown to interact with:. Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone and harboring the SL mutation responsible for a severe form of hypertension. Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to progesterone and harboring the SL mutation responsible for a severe form of hypertension.

    Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone. From Wikipedia, the free encyclopedia.

    Chromosome 4 human [1]. Mineralocorticoids and antimineralocorticoids H Desoxycortone desoxycorticosterone Desoxycortone esters Hydrocortisone cortisol Hydrocortisone esters Fludrocortisone Fludrocortisone acetate Methylprednisolone Methylprednisolone esters Prednisolone Prednisolone esters Prednisone Prednisone esters. Mineralocorticoid Receptor with Bound Deoxycorticosterone. Transcription factors and intracellular receptors.

    A B C Octamer transcription factor: Retrieved from " https: Genes on human chromosome 4 Intracellular receptors Transcription factors Human proteins. Views Read Edit View history. This page was last edited on 11 June , at By using this site, you agree to the Terms of Use and Privacy Policy. Available structures PDB Ortholog search: Chromosome 8 mouse [2].

    More reference expression data. Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone and harboring the SL mutation responsible for a severe form of hypertension 1ya3: Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to progesterone and harboring the SL mutation responsible for a severe form of hypertension 2a3i: Mineralocorticoid Receptor with Bound Aldosterone 2aa5: Mineralocorticoid Receptor with Bound Progesterone 2aa6: Mineralocorticoid Receptor with Bound Deoxycorticosterone 2aax: Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone 2gda:

    Mineralocorticoid - Wikipedia

    mineralocorticoid wiki

    Mineralocorticoid receptor - Wikipedia

    mineralocorticoid wiki

    all_steroid_drugs [TUSOM | Pharmwiki]

    mineralocorticoid wiki