Crazy Bulk Review – Detailed and HonestVitiligo is an acquired, often hereditary skin depigmentation disorder, characterized by discrete, well-circumscribed, chalk-white macules or patches. Upotreba kortikosteroida kod beba affects all age groups, but in more than half of kortikostetoida patients it occurs before the age of upotreba kortikosteroida kod beba, when self-image is being formed and social acceptance tbol vs anavar cycle of great importance. This is a review of vitiligo in the pediatric population, emphasizing key differences with vitiligo in adults. According to the literature reports, we suggest that children and adolescents with vitiligo, especially non-segmental type, should perform annual screening for thyroid dysfunction, particularly for parameters of autoimmune thyroiditis. Poznato je da genetski faktori imaju izvesnu ulogu u nastanku vitiliga. Izbor terapijske opcije zavisi od uzrasta bolesnika i tipa vitiliga.
Deksametazon — Википедија, слободна енциклопедија
Infantile hemangiomas are the most common, benign vascular tumors of infancy. Their main feature is spontaneous involution over months to years after an initial phase of rapid proliferation. Small, superficial lesions usually resolve without sequel, but scarring and disfigurement are still possible, while the cosmetic outcome is unpredictable. Thus, inflantile hemangiomas benefit from non-aggressive topical treatment, because it is safe and with an overall outcome comparable to spontaneous involution.
The available topical agents reported in the literature to satisfy these requirements are topical beta-blockers, imiquimod and topical corticosteroids. However, none of these have been assessed in randomized controlled trials, and standardized treatment recommendations about precise dosing and patient selection are not available yet.
Preparati za lokalu primenu koji na osnovu literaturnih podataka ispunjavaju ove kriterijume su beta-blokatori, imikvimod i kortikosteroidi. Ipak, za sve tri grupe lekova, nedostaju rezultati randomiziranih kontrolisanih ispitivanja pa samim tim i standardizovane terapijske preporuke koje se odnose na izbor pacijenata i preciznost doziranja. Beta-blokatori za lokalnu upotrebu: Ovo je lokalni neselektivni beta adrenergijski antagogonist.
Bekaplermin predstavlja faktor rasta izolovan iz trombocita. Propranolol for severe hemangiomas of infancy. N Engl J Med ; Propranolol for infantile haemangiomas: Br J Dermatol ; Pope E, Chakkittakandiyil A.
Topical timolol gel for infantile hemangiomas: Topical timolol for periocular hemangioma: Clin Pediatr Phila ; A Retrospective, Multicenter, Cohort Study. Metabolism of ophthalmic timolol: Basic Clin Pharmacol Toxicol ; Safety and efficacy of timolol in pediatric glaucoma.
Pharmacokinetics and beta-blocking effects of transdermal timolol. Eur J Clin Pharmacol ; Guo S, Ni N. Topical treatment for capillary hemangioma of the eyelid using beta-blocker solution. Mature infantile haemangiomas role for propranolol. J Eur Acad Dermatol Venereol ; Khunger N, Pahwa M. Dramatic response to topical timolol lotion of a large hemifacial infantile haemangioma associated with PHACE syndrome. Topical Propranolol Therapy for Infantile Hemangiomas.
Pediatr Dermatol ; [Epub ahead of print]. Metabolism of propranolol during percutaneous absorption in human skin. J Pharm Sci ; Interactions between novel terpenes and main components of rat and human skin: Curr Drug Deliv ;8: Topically applied imiquimod inhibits vascular tumor growth in vivo. J Invest Dermatol ; Selective impairment of TLR-mediated innate immunity in human newborns: Topical imiquimod in the treatment of infantile haemangiomas: J Am Acad Dermatol ; Clin Exp Dermatol ; Hussain W, Judge MR.
The role of imiquimod in treating infantile haemangiomas: Topical treatment of periocular capillary hemangioma. J Pediatr Ophthalmol Strabismus. Treatment of periocular capillary hemangioma with topical clobetasol propionate. Ultrapotent topical corticosteroid treatment of hemangiomas of infancy. Evaluation of topical steroids in the treatment of superficial hemangioma. Treatment of an ulcerated hemangioma with recombinant platelet-derived growth factor.
Response of ulcerated perineal hemangiomas of infancy to becaplermin gel, a recombinant human platelet-derived growth factor. Commentary on becaplermin gel Regranex for hemangiomas.
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Volume 5 Issue 4 Dec , pp. Volume 4 Issue 4 Dec , pp. Volume 3 Issue 4 Dec , pp. Volume 2 Issue 4 Dec , pp. Volume 1 Issue 4 Dec , pp. De Gruyter Online Google Scholar. Abstract Infantile hemangiomas are the most common, benign vascular tumors of infancy. Export Citation This content is open access. Have you read our house rules for communicating on De Gruyter Online?