Prednisolone 5 mg Tablets (Canada)Prednisone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Prednisone is sold per tablet and requires a prescription from your veterinarian. Prednisone is a corticosteroid, which suppresses the inflammatory response to a variety of agents. Prednisone can also be used as an immunosuppressive drug for corticosteroids dosage for dogs transplants and in cases of adrenal insufficiency Addison's disease. Without first talking to your veterinarian, don't give your pet any over-the-counter or other prescription medications while giving Prednisone. There are possible side effects, including insomnia, nausea, vomiting, corticosteroids dosage for dogs stomach, and fatigue.
Prednisone / Prednisolone for Dogs and Cats - PetPlace
Corticosteroids are among the most used and misused medications in veterinary medicine. They exert a powerful, reliable, and rapid effect, and there is no viable, more effective therapeutic alternative in animals with certain skin conditions. Topical and oral corticosteroid therapies are considered the first choice for treatment of acute and chronic inflammatory skin diseases, particularly allergic dermatitis. In addition, they aid in the inflammation associated with some types of infections, primarily Malassezia dermatitis and otitis.
Oral Corticosteroids Used in Dogs As a review, the oral corticosteroids available for dogs are listed in Table 1 along with their relative potencies, half-life, and relative mineralocorticoid effects.
As you can see from the table, these drugs' half-life becomes much longer as the potency increases. This is important from a clinical standpoint because many patients that are treated for more than two to three weeks with oral corticosteroids experience side effects.
The incidence of side effects—either annoying or more serious—increases as the potency of the corticosteroid increases. Some controversy surrounds the use of oral triamcinolone in regard to its potency and half-life. To be conservative, it is best to assume that oral triamcinolone has a greater potency than prednisone or prednisolone and has a longer biologic half-life—closer to 36 hours.
Therefore, practitioners should reserve the use of oral triamcinolone in dogs for treatment of serious refractory skin diseases. Oral dexamethasone should be used in canine cases only if no other treatment has been successful and the owners have been warned about the potential serious side effects, or the owners are debating the pet's quality of life i.
The mineralocorticoid effects of corticosteroids are responsible for increased water consumption, subsequent increased urine output, and potential urinary incontinence. Prednisone and prednisolone exert a slightly stronger mineralocorticoid effect than methylprednisolone.
Therefore, methylprednisolone may be used instead of prednisone or prednisolone in cases of undesirable increases in water consumption and urine output. The most commonly administered oral corticosteroids are prednisone and prednisolone, the latter being more effective in cats. In dogs, a short regimen of prednisone or prednisolone usually results in mild to no side effects.
Most clinicians in private practice are regularly faced with challenging dermatologic cases, and a common question arises: How much prednisone is too much? No one can definitively answer this question, as different dogs respond in different ways. Some patients are unaffected by long-term prednisone administration, while others immediately demonstrate polyphagia, polydipsia and polyuria, or incontinence. Still others show signs of iatrogenic Cushing's disease—muscle wasting, a pot-bellied appearance, and muscle weakness—early on in therapy.
The best approach is to try the safest treatment first, monitor the patient's response carefully, and adjust the therapeutic protocol if side effects become problematic or the condition does not respond. Many dogs receiving corticosteroids will experience alterations in blood work, including variable increases in alkaline phosphatase activity; stress leukograms characterized by neutrophilia, lymphopenia, and eosinopenia; hyperglycemia; hypercholesterolemia; and occasionally a blunted cortisol response to adrenocorticotropic hormone ACTH administration.
Other side effects commonly seen with long-term therapy include weight gain, a pot-bellied appearance associated with fat redistribution, alopecia some hairs fracture, but most are arrested in the telogen phase , thin and poorly elastic skin, comedones, pustules, and secondary bacterial infections primarily involving the skin and the urinary tract.
In one study, more than one-third of dogs experienced a urinary tract infection when treated with corticosteroids for longer than six months. Anesthesia Atopic dermatitis Canine cranial cruciate ligament injuries Canine and feline lymphoma Canine house training Canine hyperadrenocorticism Canine influenza Chronic and acute renal disease Cognitive dysfunction Congestive heart failure Diabetes mellitus Feline hyperthyroidism Feline inappropriate elimination Fleas Food allergy Gastric dilatation-volvulus Geriatric medicine Glaucoma Heartworm disease Leptospirosis Low-stress techniques Nutrition nuggets Obesity in pets Osteoarthritis Otitis Pancreatitis and gastrointestinal disease Periodontal disease Separation anxiety Ticks Urinary tract disease Wound management and skin grafts.
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A day of tragedy and heroism. Using oral corticosteroids Table 1. Oral Corticosteroids Used in Dogs.