Understanding Anabolic and Androgenic PropertiesI have been researching this heavily in hopes of critiquing my tren prohormone pct next run. The androgenic anabolic ratio explained is to steer clear of heavy androgens. We have an idea of what she wants to run but I thought this may be useful to some androgenic anabolic ratio explained since I have yet to see it here. This was found on a number of different sites and is universally accepted. However the importance and usefulness of these numbers is up for debate. The levator ani is not a skeletal muscle, but is analogous to the human PCG muscle.
Steroids Forum: Steroids QA/Anabolic Steroids/Anabolic vs androgenic ratios
Much of the focus here on Steroidal. It is very important for any anabolic steroid user to understand what these values are, what they mean, and how they were originally derived so that people know exactly what they are dealing with.
Very often are the anabolic: Firstly, all anabolic steroids have two primary effects on any vertebrate organism: It should be basic knowledge to most who are reading this right now that anabolic effects are the muscle growth promoting effects, and the androgenic effects are the masculinizing effects such as the deepening of the voice, growth of facial and bodily hair, etc.
In order for a steroid to be considered an anabolic, it must have a greater affinity to produce more muscle growth anabolism than it does androgenic effects. For example, some synthetic steroids that were created during the anabolic steroid development boom from the s to the late s exhibited an anabolic rating of 0, while the androgenic rating was much higher.
These obviously would be classified as strictly androgenic steroids, and it is also quite obvious why these compounds never surfaced with any degree of popularity among athletes and bodybuilders. Because both of the anabolic and androgenic effects expressed by anabolic steroids are mediated via the androgen receptor, often times a reduction in the androgenic strength of a compound will also be met with a reduction in anabolic strength.
Similarly, not all anabolic properties of anabolic steroids are exhibited through the androgen receptor, which would explain why some compounds in reality seem weaker than their anabolic: These are examples where the reality is different from the numbers and figures on paper, and other non-receptor mediated properties of the given anabolic steroid need to be taken into consideration.
This is indeed the case with many different synthetic derivatives of Testosterone. Of course this was never the case, as I have previously mentioned that the anabolic and androgenic effects of anabolic steroids are inseparable. At the same time in the s, a system needed to be designed whereby the different anabolic steroids created needed to be tested as well as held to a particular standard of measurement of strength.
This is much like how temperature, for example, utilizes the Fahrenheit or Celsius scales of measurement. And much like how the Celsius scale utilizes the freezing and boiling point of water 0 and degrees respectively as the standard, this system would utilize Testosterone as the standard by which all other anabolic steroids would be measured to.
In the case of orally administered anabolic steroids, Methyltestosterone would be the standard. This system involved the administration of anabolic steroids on rats, either orally or by injection depending on the anabolic steroid being assessed. This was known as the Hershberger Assay. After administration, various body parts and muscles of the rats would be analyzed such as the levator ani, seminal vesicles, and ventral prostate.
These tissues would be compared to the size of tissues that were exposed to the standard either Testosterone or Methyltestosterone, depending on whether the anabolic steroid being assayed was oral or injectable. The levator ani, for example, is a muscle in animals with tails that propels the tail in a wagging motion. The seminal vesicles as well as the ventral prostate are tissues that contain a high concentration of androgen receptors and are very sensitive to androgenic effects, and so any growth observed in those tissues would indicate the propensity for a compound to exert androgenic effects in an organism or tissue.
It is through the Hershberger Assay and the markers explained above that science attempted to generate an anabolic steroid that would exhibit a high anabolic value and a low androgenic value. In the s, a scientist by the name of Julius Vida took the time to review and compile all of the known data at the time, and published a book that described all of these values and characteristics of the known anabolic steroids in detail.
Lastly, it is important to understand that these values are not the end-all-be-all in determining the capabilities of an anabolic steroid. But they should be the first place to start when reading and researching different compounds. The figures discovered using the Hershberger Assay provides us a general and reasonable idea of the anabolic and androgenic qualities of a given anabolic steroid.
Within science and medicine, these are the very first initial tests that are conducted when a new anabolic steroid is discovered or developed in order to determine whether or not further testing and research into a particular anabolic steroid is worth the time and effort or not.
If the Hershberger Assay of a given anabolic steroid provides desirable anabolic and androgenic values, it would likely progress to the next stage of testing, and ultimately towards human clinical trials.
Dan's educational emphasis is on performance enhancement drugs PEDs , endocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Dan has had an interest in learning and writing about steroid use for over 15 years. Next Fenugreek Boosts Testosterone.