Public Enemy #1 for Male Fertility: Anabolic SteroidsFor several decades, testosterone and its synthetic derivatives have been used anabolic steroids male infertility anabolic and androgenic purposes. These substances were first restricted to professional bodybuilders, but become more and more popular among recreational infertolity. Up to date, 3, anabolic-androgenic steroids AAS users have anabolic steroids male infertility reported in the United States with an increasing prevalence, making Inferitlity consumption a major public health monounsaturated fat boost testosterone concern. Several conditions may be related to male infertility. Substance abuse, including AAS, is commonly associated to transient or persistent impairment on male reproductive function, through different pathways.
Anabolic steroids abuse and male infertility
Seeking for hypermusculation can lead to the development of problems to conceive children, i. Steroids are a group of lipid molecules whose base is cholesterol and that can be naturally found in the body. Among the sexual hormones are included the following: Among them are also included vitamin D and hormones related to stress, such as glucotiroids, cortisol, and corticosterone. These molecules turn into one another depending on the needs of the organism, which means they are related to each other.
An effect of testosterone in particular is an increasing the body mass. That is why artificial anabolic steroids have been developed, which are analogue molecules of steroids that can be taken orally or injected and provoke a rapid increase of the muscular mass. As a consequence, they have become very famous in the search for a fast increase of male muscular mass. Steroids have reversible and irreversible side effects.
Since the estrogenic hormone and the testosterone come from the same metabolic route, an increase in the estrogenic hormone instead of testosterone can take place and is not what is intended. This would result in a growth of the breasts in the men gynecomastia , baldness, aggressiveness, or changes in the voice deepness in women. For the formation of the spermatozoa , the hypothalamus located in the brain cortex sends an order to the pituitary gland that has the shape of a pea and is located under the cerebellum , which expels the hormones required for the spermatogenesis: LH luteinizing hormone and FSH follicle-stimulating hormone.
The formation of the spermatozoa is followed by an increase in the concentration of testosterone that acts on the hypothalamus, reducing the production of LH and FSH and controlling spermatogenesis. This means that the high concentration of testosterone acts on the hypothalamus-pituitary gland-testicle axis to stop sperm production. This happens in a natural way but when the steroids rate increases artificially, testosterone in this case, the organism detects this increase in the concentration of this hormone and receives the order of stopping spermatogenesis.
This way the production of spermatozoa in the seminiferous tubules located inside the testicles stops. The testicles stop the production of gametes and become smaller, since part of the testicular volume depends on the seminiferous tubules and the formation of spermatozoa. This hormonal alteration can be reversed by eliminating the external steroids source, but at least two months will be needed for the testicular function to return to normality.
Pre-testicular causes of male infertility Sertoli cell-only syndrome Anabolic steroids and male fertility: If you abide by the rules, it is good, the abuse is bad. Do not listen to others say but evaluate something. You must be logged in to post a comment. Anabolic steroids and male fertility: Side effects of anabolic steroids. Artificial testosterone reduces fertility.
Shrinkage of the testicles because of anabolic agents. Every thing has two sides: Log in to Reply. Cookies allow us to show customized advertising and collect statistical data. By continuing to use our website, you are agreeing to our cookies policy.